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Diphtheria | Collections | MSF Science Portal
Diphtheria

Diphtheria

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Expanding access to lifesaving new TB tools

Expanding access to lifesaving new TB tools
Many settings with a high burden of drug-resistant tuberculosis (DR-TB) lack access to advanced diagnostics and to groundbreaking new treatments. The Collection linked below spotlights work by MSF and collaborators to analyze barriers, identify gaps, and accelerate the roll-out of these tools to people whose lives hang in the balance. Several reports examine price, regulatory, and patent obstacles that persist despite considerable public investment into developing many of these tools. Other authors examine critical remaining weaknesses in care pathways—especially in screening and diagnosis, and particularly in children. Several studies describe new strategies that could be part of the solution, from a pilot program in Tajikisttan that trains family caregivers to treat children with DR-TB at home, to a person-centered care model adapted to a conflict zone in Afghanistan. Lastly, initial findings demonstrate that pregnant women—another vulnerable population—can be effectively treated for DR- and multidrug-resistant TB, improving maternal outcomes without harming neonates.
ASTMH Annual Meeting 2024

ASTMH Annual Meeting 2024

The American Society of Tropical Medicine & Hygiene (ASTMH) Annual Meeting is an international forum for the exchange of scientific and clinical advances in tropical medicine, hygiene and global health. The scientific content this year is 53% microbe focused, 15% clinically focused, 13% vector focused, 13% globally focused, and 6% intervention focused.

MSF and Epicentre are presenting on access and other challenges for children with visceral and cutaneous leishmaniasis, hurdles in malaria diagnostic testing, and ensuring equitable access to healthcare in conversations about financial sustainability.

This collection features research authored by the presenters and other topics highlighted at ASTMH.

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Sudan/Chad Disaster
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Journal Article
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Short Report

Diphtheria in Europe

Mangion JP, Mancini S, Bachy C, de Weggheleire A, Zamatto F
2023-06-21 • Public Health Action
2023-06-21 • Public Health Action
A rising number of diphtheria cases were recorded in Europe in 2022, including in Belgium, within the newly arriving young migrant population. In October 2022, Médecins Sans Frontières (...
Journal Article
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Research

Diphtheria antitoxin administration, outcomes, and safety: response to a diphtheria outbreak in Cox’s Bazar, Bangladesh

Eisenberg N, Panunzi I, Wolz A, Burzio C, Cilliers A,  et al.
2021-10-05 • Clinical Infectious Diseases
2021-10-05 • Clinical Infectious Diseases
BACKGROUND
Diphtheria has re-emerged over the past several years. There is a paucity of data on the administration and safety of diphtheria antitoxin (DAT), the standard treatment fo...
Journal Article
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Research

Evaluation of community based surveillance in the Rohingya refugee camps in Cox’s Bazar, Bangladesh, 2019

Van Boetzelaer E, Chowdhury SM, Etsay B, Faruque A, Lenglet AD,  et al.
2020-12-23 • PLOS One
2020-12-23 • PLOS One
BACKGROUND
Following an influx of an estimated 742,000 Rohingya refugees in Bangladesh, Médecins sans Frontières (MSF) established an active indicator-based Community Based Surveilla...
Journal Article
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Commentary

Caring for Rohingya refugees with diphtheria and measles: on the ethics of humanity

Asgary R
2020-03-01 • Annals of Family Medicine
2020-03-01 • Annals of Family Medicine
Hundreds of thousands of Rohingya refugees arrived in Bangladesh within weeks in fall 2017, quickly forming large settlements without any basic support. Humanitarian first responders pro...
Journal Article
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Review

Clinical and epidemiological aspects of diphtheria: a systematic review and pooled analysis

Truelove SA, Keegan LT, Moss WJ, Chaisson LH, Macher E,  et al.
2019-08-19 • Clinical Infectious Diseases
2019-08-19 • Clinical Infectious Diseases
BACKGROUND
Diphtheria, once a major cause of childhood morbidity and mortality, all but disappeared following introduction of diphtheria vaccine. Recent outbreaks highlight the risk ...
Conference Material
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Poster

Diphtheria in an emergency outbreak setting: a clinical and epidemiological analysis for children and adults, Bangladesh

Sikder E, del Barrio BV, Firuz W, Khatoon R, Opstrup A,  et al.
2019-04-29 • MSF Scientific Days International 2019
2019-04-29 • MSF Scientific Days International 2019
Journal Article
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Research

Real-time analysis of the diphtheria outbreak in forcibly displaced Myanmar nationals in Bangladesh

Finger F, Funk S, White K, Siddqui MR, Edmunds KL,  et al.
2019-03-12 • BMC Medicine
2019-03-12 • BMC Medicine
Between August and December 2017, more than 625,000 Rohingya from Myanmar fled into Bangladesh, settling in informal makeshift camps in Cox’s Bazar district and joining 212,000 Rohingya ...
Protocol
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Research Protocol

Vaccination coverage survey for diphtheria, Streptococcus pneumoniae, polio and tetanus in Rohingya refugee settlements in Ukhiya and Teknaf Upazilas, Cox’s Bazar, Bangladesh

Pereboom M, White K, Van Leeuwen C, Siddiqui R, Guzek J,  et al.
2018-07-01
2018-07-01
OBJECTIVES

PRIMARY OBJECTIVES
a) To describe the vaccine coverage (penta / dT) in children aged 6 months to 14 years for diphtheria in the Rohingya Settlement Camps;
Journal Article
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Review

The preventable tragedy of diphtheria in the 21st century

Blumberg LH, Prieto MA, Diaz JV, Blanco MJ, Valle B,  et al.
2018-06-08 • International Journal of Infectious Diseases
2018-06-08 • International Journal of Infectious Diseases
Journal Article
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Research

Diphtheria outbreak with high mortality in northeastern Nigeria

Besa NC, Coldiron ME, Bakri A, Raji A, Nsuami MJ,  et al.
2013-07-18 • Epidemiology and Infection
2013-07-18 • Epidemiology and Infection
SUMMARY A diphtheria outbreak occurred from February to November 2011 in the village of Kimba and its surrounding settlements, in Borno State, northeastern Nigeria. We conducted a retros...