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Showing 1 - 13 of 13 Items
Showing 1 - 13 of 13 Items
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Research

Centrifuge-free stool processing methods for Xpert MTB/RIF Ultra tuberculosis diagnosis in children in Uganda and Zambia: an observational, prospective, diagnostic accuracy study

Lounnas M, Masama EN, Beneteau S, Kasakwa K, Kaitano R,  et al.
2025-06-01 • Lancet Microbe
2025-06-01 • Lancet Microbe

BACKGROUND

WHO recommends Xpert MTB/RIF Ultra (Ultra) for stool testing for tuberculosis diagnosis in children. Stool processing requires removal of debris and ...

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Commentary
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Research
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Research
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Research
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Journal Article
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Commentary

Keeping our feet on the ground: the role of innovation in scaling up diagnosis to counter antimicrobial resistance

Alkon A, Cunningham J, Kanapathipillai R, Naim C, Shortall C,  et al.
2025-05-01 • Lancet Microbe
2025-05-01 • Lancet Microbe

Effectiveness of the primary Bacillus Calmette-Guérin vaccine against the risk of Mycobacterium tuberculosis infection and tuberculosis disease: a meta-analysis of individual participant data

Pelzer PT, Stuck L, Martinez L, Richards AS, Acuña-Villaorduña C,  et al.
2024-12-19 • Lancet Microbe
2024-12-19 • Lancet Microbe

BACKGROUND

Tuberculosis vaccine trials using disease as the primary endpoint are large, time consuming, and expensive. An earlier immunological measure of the p...

WHO global research priorities for antimicrobial resistance in human health

Bertagnolio S, Dobreva Z, Centner CM, Olaru ID, Dona D,  et al.
2024-08-12 • Lancet Microbe
2024-08-12 • Lancet Microbe

Importance of investing time and money in integrating large language model-based agents into outbreak analytics pipelines

van Hoek AJ, Funk S, Flasche S, Quilty BJ, van Kleef E,  et al.
2024-08-01 • Lancet Microbe
2024-08-01 • Lancet Microbe

Bedaquiline resistance in patients with drug-resistant tuberculosis in Cape Town, South Africa: a retrospective longitudinal cohort study

Derendinger B, Dippenaar A, de Vos M, Huo S, Alberts R,  et al.
2023-12-01 • Lancet Microbe
2023-12-01 • Lancet Microbe
BACKGROUND
Bedaquiline is a life-saving tuberculosis drug undergoing global scale-up. People at risk of weak tuberculosis drug regimens are a priority for novel drug access despite t...

Effect of amoxicillin on the gut microbiome of children with severe acute malnutrition in Madarounfa, Niger: a retrospective metagenomic analysis of a placebo-controlled trial

Schwartz DJ, Langdon A, Sun X, Langendorf C, Berthé F,  et al.
2023-10-19 • Lancet Microbe
2023-10-19 • Lancet Microbe
BACKGROUND
Children with severe acute malnutrition are treated with antibiotics as outpatients. We aimed to determine the effect of 7 days of amoxicillin on acute and long-term chang...

Diagnostics to support the scaling up of shorter, safer tuberculosis regimens

Branigan D, Denkinger CM, Furin J, Heitkamp P, Deborggraeve S,  et al.
2023-07-31 • Lancet Microbe
2023-07-31 • Lancet Microbe

Effect of compensatory evolution in the emergence and transmission of rifampicin-resistant Mycobacterium tuberculosis in Cape Town, South Africa: a genomic epidemiology study

Goig GA, Menardo F, Salaam-Dreyer Z, Dippenaar A, Streicher EM,  et al.
2023-06-06 • Lancet Microbe
2023-06-06 • Lancet Microbe
BACKGROUND
Experimental data show that drug-resistance-conferring mutations are often associated with a decrease in the replicative fitness of bacteria in vitro, and that this fitnes...

Potential contribution of HIV during first-line tuberculosis treatment to subsequent rifampicin-monoresistant tuberculosis and acquired tuberculosis drug resistance in South Africa: a retrospective molecular epidemiology study

Cox HS, Salaam-Dreyer Z, Goig GA, Nicol MP, Menardo F,  et al.
2021-11-01 • Lancet Microbe
2021-11-01 • Lancet Microbe
BACKGROUND
South Africa has a high burden of rifampicin-resistant tuberculosis (including multidrug-resistant [MDR] tuberculosis), with increasing rifampicin-monoresistant (RMR) tube...

Biphasic versus monophasic manual blood culture bottles for low-resource settings: an in-vitro study

Ombelet S, Natale A, Ronat JB, Kesteman T, Vandenberg O,  et al.
2021-12-13 • Lancet Microbe
2021-12-13 • Lancet Microbe
BACKGROUND
Manual blood culture bottles (BCBs) are frequently used in low-resource settings. There are few BCB performance evaluations, especially evaluations comparing them with aut...

Leaving no one behind: the need for a truly global response to antimicrobial resistance

Goldberg J, Clezy K, Jasovský D, Uyen-Cateriano A
2022-01-01 • Lancet Microbe
2022-01-01 • Lancet Microbe

The Mini-Lab: accessible clinical bacteriology for low-resource settings

Natale A, Ronat JB, Mazoyer A, Rochard A, Boillot B,  et al.
2020-06-01 • Lancet Microbe
2020-06-01 • Lancet Microbe